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課程名稱 |
藥物傳輸系統
Drug Delivery Systems |
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開課學期 |
109-1 |
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授課對象 |
學程 奈米科技學程 |
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授課教師 |
黃義侑 |
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課號 |
DBME7014 |
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課程識別碼 |
528 M0300 |
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班次 |
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學分 |
3.0 |
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全/半年 |
半年 |
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必/選修 |
選修 |
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上課時間 |
星期一2,3,4(9:10~12:10) |
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上課地點 |
基醫505 |
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備註 |
本課程中文授課,使用英文教科書。
總人數上限：30人 |
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Ceiba 課程網頁 |
http://ceiba.ntu.edu.tw/1091DBME7014_ |
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課程簡介影片 |
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核心能力關聯 |
核心能力與課程規劃關聯圖 |
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課程大綱
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課程概述 |
一、課程簡介:
To provide the students with a broad spectrum of scientific information in a concise, systematic manner but with new vision and wider scope in drug delivery systems. Lectures include:
1. Concepts and System Design forthe Rate-Controlled Drug Delivery
2. Mathematical Modeling of Controlled Drug Delivery
3. Oral Drug Delivery and Delivery System
4. Mucosal Drug Delivery: Potential Routes for Noninvasive Systemic
Administration (Rectal & Oral musosa DDS)
5. Nasal/ Pulmonary Drug Delivery and Delivery System
6. Transdermal Drug Delivery and Delivery System
7. Ocular Drug Delivery and Delivery System
8. Polymers for Drug delivery, EVA, Silicone...
and Natural Biodegradable Polymer in Drug Delivery System
9. Synthetic Biodegradable Polymer in Drug Delivery System
10. Compartmental Models and Their Application
11. Drug Targeting
12. Liposome Drug Delivery
13. Study Report
二、先修課程:無 |
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課程目標 |
To provide the students with a broad spectrum of scientific information in a concise, systematic manner but with new vision and wider scope in drug delivery systems. |
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課程要求 |
無 |
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預期每週課後學習時數 |
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Office Hours |
另約時間 |
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指定閱讀 |
無 |
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參考書目 |
1. A.M. Hillery, A.W. Lloyd, J. Swarbrick “Drug delivery and Targeting for
Pharmacists and Pharmaceutical Scientists ” Taylor & Francis, 2001
2. R.A. Bader, D.A. Putnam “Engineering Polymer Systems for Improved Drug Delivery”
Wiley 2014
3. J.Siepmann, R.A. Siegel, M.J. Rathbone “Fundamentals and Applications of
Controlled Release Drug Delivery” 2012 Springer
4. Polymers and Nanomaterials for Gene Therapy, Edited by:Ravin Narain 2016 |
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評量方式
(僅供參考) |
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週次 |
日期 |
單元主題 |
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第1週 |
9/14 |
L1 Introduction- What is drug delivery system?
(核心能力：2, 4, 6, 7) |
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第2週 |
9/21 |
L2 Basic concept of drug delivery-1
(核心能力：2, 6, 7) |
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第3週 |
9/28 |
L3 Basic concept of drug delivery-2
(核心能力：2, 4, 6) |
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第4週 |
10/05 |
L4 Controlled Release Mechanism
(核心能力：4, 6, 7) |
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第5週 |
10/12 |
DDS 影片教學
(核心能力：2, 3, 4) |
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第6週 |
10/19 |
L6 Implant DDS
(核心能力：2, 4, 7) |
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第7週 |
10/26 |
L7 Drug Targeting Systems:Fundamentals and
Applications to Parenteral Drug Delivery
(核心能力：2, 4, 6) |
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第8週 |
11/02 |
L8 Strategies of Drug Targeting
(核心能力：4, 6, 7) |
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第9週 |
11/09 |
Mid-term Quiz |
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第10週 |
11/16 |
L10 Ch 10 Targeted delivery using biodegradable polymeric NPs
(核心能力：3, 4, 7)
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第11週 |
11/23 |
L11 Polymer-drug conjugates
(核心能力：2, 4, 7) |
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第12週 |
11/30 |
L12 Liposomes
(核心能力：4, 6, 7) |
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第13週 |
12/07 |
Oral Presentation
(核心能力：2, 3, 4, 7) |
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第14週 |
12/14 |
Oral Presentation
(核心能力：2, 3, 4, 7) |
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第15週 |
12/21 |
Oral Presentation
(核心能力：2, 3, 4, 7) |
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第16週 |
12/28 |
Oral Presentation
(核心能力：2, 3, 4, 7) |
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第17週 |
2021/01/04 |
DDS-L17 Stimuli-Responsive DDS & Delivery of Nucleic Acids
(核心能力：2, 4, 7) |
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第18週 |
01/11 |
Final Quiz |
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